How is the VDRL test read?

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Multiple Choice

How is the VDRL test read?

Explanation:
VDRL relies on visualization of antigen–antibody flocculation. When reagin-type antibodies in the patient’s serum react with the cardiolipin-containing antigen, subtle clumping (flocculation) forms. These fine clumps are best seen with a light microscope at low magnification, so the test is read microscopically. Color change, fluorescence, or turbidity aren’t used to determine VDRL results—the test detects specific aggregation patterns rather than a color, glow, or cloudiness.

VDRL relies on visualization of antigen–antibody flocculation. When reagin-type antibodies in the patient’s serum react with the cardiolipin-containing antigen, subtle clumping (flocculation) forms. These fine clumps are best seen with a light microscope at low magnification, so the test is read microscopically. Color change, fluorescence, or turbidity aren’t used to determine VDRL results—the test detects specific aggregation patterns rather than a color, glow, or cloudiness.

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